Effects of dexamethasone and celecoxib on calcium homeostasis and expression of cyclooxygenase-2 mRNA in MG-63 human osteosarcoma cells.

Abstract

OBJECTIVE Glucocorticoids and selective COX-2 inhibitors are potent anti-inflammatory agents. They are also suggested to influence bone physiology and remodeling. Here we searched for effects of dexamethasone and celecoxib on crucial parameters of bone physiology that could be therapeutically relevant. METHODS The human osteosarcoma cell line MG-63 was… (More)

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@article{Wiontzek2006EffectsOD, title={Effects of dexamethasone and celecoxib on calcium homeostasis and expression of cyclooxygenase-2 mRNA in MG-63 human osteosarcoma cells.}, author={M Wiontzek and Georg Matziolis and Sebastian Schuchmann and Timo Gaber and Doerte Krocker and G N Duda and G R Burmester and Carsten Perka and Frank Buttgereit}, journal={Clinical and experimental rheumatology}, year={2006}, volume={24 4}, pages={366-72} }