Effects of deregulation of methionine biosynthesis on methionine excretion in Escherichia coli.

@article{Usuda2005EffectsOD,
  title={Effects of deregulation of methionine biosynthesis on methionine excretion in Escherichia coli.},
  author={Yoshihiro Usuda and Osamu Kurahashi},
  journal={Applied and environmental microbiology},
  year={2005},
  volume={71 6},
  pages={3228-34}
}
Several regulators of methionine biosynthesis have been reported in Escherichia coli, which might represent barriers to the production of excess l-methionine (Met). In order to examine the effects of these factors on Met biosynthesis and metabolism, deletion mutations of the methionine repressor (metJ) and threonine biosynthetic (thrBC) genes were introduced into the W3110 wild-type strain of E. coli. Mutations of the metK gene encoding S-adenosylmethionine synthetase, which is involved in Met… CONTINUE READING

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