Effects of deracoxib or buffered aspirin on the gastric mucosa of healthy dogs.

@article{Sennello2006EffectsOD,
  title={Effects of deracoxib or buffered aspirin on the gastric mucosa of healthy dogs.},
  author={Kathleen A Sennello and Michael S. Leib},
  journal={Journal of veterinary internal medicine},
  year={2006},
  volume={20 6},
  pages={1291-6}
}
BACKGROUND Use of cyclo-oxygenase-2 specific nonsteroidal anti-inflammatory drugs such as deracoxib has been advocated because of their anti-inflammatory actions and apparently low incidence of gastrointestinal adverse effects. HYPOTHESIS Deracoxib will cause less endoscopically detectable gastric injury in dogs than aspirin, a nonselective nonsteroidal anti-inflammatory drug. ANIMALS Twenty-four random source healthy dogs. METHODS A randomized, placebo-controlled trial compared… CONTINUE READING

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Use of cyclo - oxygenase-2 specific nonsteroidal anti - inflammatory drugs such as deracoxib has been advocated because of their anti - inflammatory actions and apparently low incidence of gastrointestinal adverse effects .
Use of cyclo - oxygenase-2 specific nonsteroidal anti - inflammatory drugs such as deracoxib has been advocated because of their anti - inflammatory actions and apparently low incidence of gastrointestinal adverse effects .
Deracoxib will cause less endoscopically detectable gastric injury in dogs than aspirin , a nonselective nonsteroidal anti - inflammatory drug .
Deracoxib will cause less endoscopically detectable gastric injury in dogs than aspirin , a nonselective nonsteroidal anti - inflammatory drug .
Use of cyclo - oxygenase-2 specific nonsteroidal anti - inflammatory drugs such as deracoxib has been advocated because of their anti - inflammatory actions and apparently low incidence of gastrointestinal adverse effects .
Use of cyclo - oxygenase-2 specific nonsteroidal anti - inflammatory drugs such as deracoxib has been advocated because of their anti - inflammatory actions and apparently low incidence of gastrointestinal adverse effects .
Deracoxib will cause less endoscopically detectable gastric injury in dogs than aspirin , a nonselective nonsteroidal anti - inflammatory drug .
Median total scores for each group were compared each day of endoscopic examination and total dog - days of vomiting and diarrhea were compared .
Dogs were observed every 8 hours for vomiting and diarrhea .
Median total scores for each group were compared each day of endoscopic examination and total dog - days of vomiting and diarrhea were compared .
Dogs were observed every 8 hours for vomiting and diarrhea .
Use of cyclo - oxygenase-2 specific nonsteroidal anti - inflammatory drugs such as deracoxib has been advocated because of their anti - inflammatory actions and apparently low incidence of gastrointestinal adverse effects .
Use of cyclo - oxygenase-2 specific nonsteroidal anti - inflammatory drugs such as deracoxib has been advocated because of their anti - inflammatory actions and apparently low incidence of gastrointestinal adverse effects .
Use of cyclo - oxygenase-2 specific nonsteroidal anti - inflammatory drugs such as deracoxib has been advocated because of their anti - inflammatory actions and apparently low incidence of gastrointestinal adverse effects .
Use of cyclo - oxygenase-2 specific nonsteroidal anti - inflammatory drugs such as deracoxib has been advocated because of their anti - inflammatory actions and apparently low incidence of gastrointestinal adverse effects .
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