Effects of depletion of complement in the development of labyrinthitis ossificans.

@article{DeSautel1999EffectsOD,
  title={Effects of depletion of complement in the development of labyrinthitis ossificans.},
  author={M G DeSautel and Hilary A. Brodie},
  journal={The Laryngoscope},
  year={1999},
  volume={109 10},
  pages={1674-8}
}
HYPOTHESIS Labyrinthitis ossificans results in part from the intense inflammatory response to Streptococcus pneumoniae cell wall components. Depletion of complement in Mongolian gerbils following induction of meningitis will reduce the degree of inflammation and subsequent cochlear fibrosis. STUDY DESIGN Random prospective study. Histological evaluations were performed with the researcher blinded to the experimental group METHODS S. pneumoniae meningitis was induced in 10 control and 18… CONTINUE READING

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