Effects of denervation on cell cycle control in laryngeal muscle.

  title={Effects of denervation on cell cycle control in laryngeal muscle.},
  author={Vincent J. Caiozzo and Ya Zhen Wu and Michael J. Baker and Roger Crumley},
  journal={Archives of otolaryngology--head & neck surgery},
  volume={130 9},
Denervation of skeletal muscle is thought to lead to an accelerated proliferation of myogenic stem cells known as satellite cells. The transition of these cells from a quiescent to a proliferative state is thought to require satellite cells to enter the cell cycle and replicate. Little is known about the expression of genes associated with cell cycle control, and so the objective of this study was to examine the effects of denervation and reinnervation of the posterior cricoarytenoid (PCA… CONTINUE READING


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Aging of skeletal muscle does not affect the response of satellite cells to denervation.

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