Effects of dehydroepiandrosterone and alprazolam on hypothalamic-pituitary responses to exercise.

Abstract

CONTEXT The hypothalamic-pituitary-adrenal axis (HPA) is restrained by activation of gamma-amino-butyric acid receptors. Alprazolam (APZ) and dehydroepiandrosterone (DHEA) are purported to be gamma-amino-butyric acid agonists and antagonists, respectively. OBJECTIVE Our objective was to examine the effects of APZ and DHEA alone and in combination on HPA… (More)

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