Effects of dehydroepiandrosterone administration on rat hepatic metabolism following thermal injury.

@article{Banta2005EffectsOD,
  title={Effects of dehydroepiandrosterone administration on rat hepatic metabolism following thermal injury.},
  author={Scott Banta and Tadaaki Yokoyama and Francois Berthiaume and Martin L. Yarmush},
  journal={The Journal of surgical research},
  year={2005},
  volume={127 2},
  pages={93-105}
}
BACKGROUND Severe burns cause dramatic alterations in liver and whole-body metabolism. Recently, there has been interest in using dehydroepiandrosterone (DHEA) as a treatment for trauma patients, and enhanced survival and immune function have been reported using DHEA in animal trauma models. The specific effects of DHEA on hepatic metabolism following burn injury have not been explored. MATERIALS AND METHODS Male rats received either (1) a burn covering approximately 20% of the total body… CONTINUE READING