Effects of deficiency of active vitamin D on bone marrow ablation of femur in mice.

@article{Wu2019EffectsOD,
  title={Effects of deficiency of active vitamin D on bone marrow ablation of femur in mice.},
  author={Jian Wu and Qi Zhang and Shengjun Qian and Ling-Ling Jin and Zhang Ying and D H Cao},
  journal={Journal of biological regulators and homeostatic agents},
  year={2019},
  volume={33 1},
  pages={
          109-117
        }
}
The aim of this study was to investigate the effect of active vitamin D deficiency on bone marrow ablation (BMX) repair in mice. Six-week-old α(OH)ase knockout [1α(OH)ase-/-] mice and control wild type mice were used to generate the BMX model. Serum Ca, P and PTH (parathyroid hormone) concentration were determined at 0 week (before operation), 1 week (1W), 2 weeks (2W) and 3 weeks (3W) post-operation. Callus formation and absorption 1W, 2W and 3W post-operation were observed by imaging and… CONTINUE READING