Effects of deep brain stimulation and medication on bradykinesia and muscle activation in Parkinson's disease.

@article{Vaillancourt2004EffectsOD,
  title={Effects of deep brain stimulation and medication on bradykinesia and muscle activation in Parkinson's disease.},
  author={David E. Vaillancourt and Janey Prodoehl and Leo Verhagen Metman and R. Bakay and Daniel M. Corcos},
  journal={Brain : a journal of neurology},
  year={2004},
  volume={127 Pt 3},
  pages={491-504}
}
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) and antiparkinsonian medication (Meds) have proved to be effective therapies for treating bradykinesia in Parkinson's disease. However, it is not currently known how or to what extent STN stimulation alters the control signals to agonist and antagonist muscles to change movement speed. Our objective was to investigate movement speed along with the amplitude and temporal features of EMG activity to determine how and to what extent… CONTINUE READING

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