Effects of damage in the articular surface on the cartilage response to injurious compression in vitro.

@article{Morel2006EffectsOD,
  title={Effects of damage in the articular surface on the cartilage response to injurious compression in vitro.},
  author={V{\'e}ronique Morel and Carine Berutto and T M Khayat Quinn},
  journal={Journal of biomechanics},
  year={2006},
  volume={39 5},
  pages={924-30}
}
Macroscopic structural damage to the cartilage articular surface can occur due to slicing in surgery, cracking in mechanical trauma, or fibrillation in early stage osteoarthrosis. These alterations may render cartilage matrix and chondrocytes susceptible to subsequent mechanical injury and contribute to progression of degenerative disease. To examine this hypothesis, single 300 microm deep vertical slices were introduced across a diameter of the articular surface of osteochondral explant disks… CONTINUE READING