Effects of d-amphetamine and caffeine in humans under a cocaine discrimination procedure.

@article{Oliveto1998EffectsOD,
  title={Effects of d-amphetamine and caffeine in humans under a cocaine discrimination procedure.},
  author={Alison H Oliveto and Elinore F McCance-Katz and Amrita K. Singha and Faig A Hameedi and Thomas R. Kosten},
  journal={Behavioural pharmacology},
  year={1998},
  volume={9 3},
  pages={207-17}
}
This study examined further the pharmacological specificity of an oral cocaine discriminative stimulus in humans. Five male cocaine-abusing volunteers (two African-American/three Caucasian) were trained to discriminate between a low dose of cocaine hydrochloride (80 mg/70 kg, p.o.) and placebo. Once the criterion for discrimination was met (i.e. > or = 80% correct responding for four consecutive sessions), dose-effect curves were determined for the dopamine reuptake inhibitor cocaine (20, 40… CONTINUE READING

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