Effects of cytokines on gingival fibroblasts in vitro are modulated by the extracellular matrix.

Abstract

Fibroblast function in gingival tissue is thought to be regulated by the local cellular environment--both the extracellular matrix and soluble factors. In an attempt to artificially re-create this situation fibroblasts have been cultured within 3-dimensional collagen gels in an environment more physiologically comparable to connective tissue. Using such a… (More)

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Cite this paper

@article{Irwin1994EffectsOC, title={Effects of cytokines on gingival fibroblasts in vitro are modulated by the extracellular matrix.}, author={Chris R. Irwin and Seth L. Schor and Mark W. J. Ferguson}, journal={Journal of periodontal research}, year={1994}, volume={29 5}, pages={309-17} }