Effects of cytokines from activated immune cells on vascular cell growth and HIV-1 gene expression. Implications for AIDS-Kaposi's sarcoma pathogenesis.

@article{Barillari1992EffectsOC,
  title={Effects of cytokines from activated immune cells on vascular cell growth and HIV-1 gene expression. Implications for AIDS-Kaposi's sarcoma pathogenesis.},
  author={Giovanni Barillari and Luigi Buonaguro and Valeria Fiorelli and Jennifer R Hoffman and Frank H. Michaels and Robert C. Gallo and Barbara Ensoli},
  journal={Journal of immunology},
  year={1992},
  volume={149 11},
  pages={3727-34}
}
Kaposi's sarcoma (KS) arises more frequently in homosexual and bisexual men than in other groups of HIV-1 infected individuals. Clinico-epidemiologic data indicate that homosexuals often are infected with multiple microbial agents and/or subjected to other antigenic stimuli, preceding or accompanying HIV-1 infection. Signs of immune activation, in fact, frequently have been detected in these individuals, and the onset of KS can precede any sign of immunodeficiency. These data have suggested… CONTINUE READING
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