Corpus ID: 34304040

Effects of cyproterone on the steroid biosynthesis in the human ovary in vitro.

@article{Schrenkmper1982EffectsOC,
  title={Effects of cyproterone on the steroid biosynthesis in the human ovary in vitro.},
  author={P. Sch{\"u}renk{\"a}mper and K. Lisse},
  journal={Endokrinologie},
  year={1982},
  volume={80 3},
  pages={
          281-6
        }
}
To examine the direct effects of cyproterone on the ovarian biosynthesis of steroids, tissue slices obtained from two cyclically functional human ovaries were incubated with [4-14C]pregnenolone as precursor. The steroid production was determined by measuring the concentration of eleven 14C-labelled steroids in the medium at the end of a 3-h incubation. Under control conditions, the in vitro-synthesis of 17 alpha-hydroxypregnenolone, dehydroepiandrosterone, androstenediol (5-ene-3 beta-hydroxy… Expand