Effects of cyclosporin A on suppressor and inducer T lymphocytes in primary biliary cirrhosis.

@article{Routhier1980EffectsOC,
  title={Effects of cyclosporin A on suppressor and inducer T lymphocytes in primary biliary cirrhosis.},
  author={G Routhier and Owen Epstein and George Janossy and Howard Thomas and Sherlock and Patrick Kung and Gideon Goldstein},
  journal={Lancet},
  year={1980},
  volume={2 8206},
  pages={1223-6}
}
There is a significant decrease in the ratio of inducer (helper) to suppressor T lymphocytes in the peripheral blood of patients with primary biliary cirrhosis (PBC). These changes are not seen in other forms of cholestatic liver disease, but are similar to those described in chronic graft-versus-host disease. Cyclosporin A treatment increased the… CONTINUE READING