Effects of cyclophosphamide on lesions induced by persistent LCM virus infection in gnotobiotic mice

Cyclophosphamide (CP) has shown therapeutic benefits for treatment of immnoproliferative disease associated with persistent LCM virus infection. Depending on the age of LCM mice at onset of the treatment, the classical lesions were prevented or reversed by treatment with the drug. Reappearance of lesions following cessation of treatment coincided with the… CONTINUE READING