Effects of cyclic AMP altering drugs on endotoxin-induced termination of pregnancy.

Abstract

The effects of dibutyryl-cyclic AMP (DBcAMP), propranolol, and theophylline on endotoxin (LPS) challenged pregnant mice was determined by comparing the patterns of termination and times of fetal expulsion. Endotoxin isolated from wild type (WT) and Re chemotype mutant cells of Salmonella typhimurium was used. Wild type LPS caused the expulsion of the… (More)

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