Effects of current and former cigarette smoking on the clinical course of Crohn’s disease

@article{Cosnes1999EffectsOC,
  title={Effects of current and former cigarette smoking on the clinical course of Crohn’s disease},
  author={Cosnes and Carbonnel and Carrat and Beaugerie and Cattan and Gendre},
  journal={Alimentary Pharmacology \& Therapeutics},
  year={1999},
  volume={13}
}
  • Cosnes, Carbonnel, Gendre
  • Published 1 November 1999
  • Medicine, Psychology
  • Alimentary Pharmacology & Therapeutics
: Cigarette smoking is associated with a more severe course of Crohn’s disease, but individual factors determining this effect are poorly known and it is not clear whether smoking cessation is associated with an improvement in the disease activity. 
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Smoking is the best‐characterised environmental association of ulcerative colitis (UC). Smoking has been observed to exert protective effects on both the development and progression of UC.
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Impact of smoking on the surgical outcome of Crohn's disease: a propensity‐score matched National Surgical Quality Improvement Program analysis
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The present study addressed the specific impact of smoking on the outcome of surgery for CD with a focus on smokers with Crohn's disease.
Review article: altering the natural history of Crohn's disease – evidence for and against current therapies
TLDR
The natural course of Crohn's disease is characterized by flare‐ups altered with periods of remission, but major advances in treatment options over the past years have made treatment goals more ambitious and modification of the natural course has become the ultimate endpoint.
Impact of Smoking Cessation on the Clinical Course of Crohn’s Disease Under Current Therapeutic Algorithms: A Multicenter Prospective Study
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Continuing smokers have more disease relapses, and patients who quit smoking have a similar relapse incidence compared with nonsmokers, as evaluated in a multicenter prospective cohort study.
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