Effects of crystalloids and colloids on liver and intestine microcirculation and function in cecal ligation and puncture induced septic rodents

@inproceedings{Schick2012EffectsOC,
  title={Effects of crystalloids and colloids on liver and intestine microcirculation and function in cecal ligation and puncture induced septic rodents},
  author={Martin Alexander Schick and Jobst Tobias Isbary and Tanja Nadine Stueber and Juergen Brugger and Jan Stumpner and Nicolas Schlegel and Norbert Roewer and Otto Eichelbroenner and Christian Wunder},
  booktitle={BMC gastroenterology},
  year={2012}
}
BackgroundSeptic acute liver and intestinal failure is associated with a high mortality. We therefore investigated the influence of volume resuscitation with different crystalloid or colloid solutions on liver and intestine injury and microcirculation in septic rodents.MethodsSepsis was induced by cecal ligation and puncture (CLP) in 77 male rats. Animals were treated with different crystalloids (NaCl 0.9% (NaCl), Ringer’s acetate (RA)) or colloids (Gelafundin 4% (Gel), 6% HES 130/0.4 (HES… CONTINUE READING
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