Effects of creatine supplementation and exercise training on fitness in men 55-75 yr old.

  title={Effects of creatine supplementation and exercise training on fitness in men 55-75 yr old.},
  author={Bert O. Eijnde and Marc van Leemputte and Marina Goris and Valery Labarque and Youri E. C. Taes and Patricia Verbessem and Luc Vanhees and Monique Ramaekers and Bart Vanden Eynde and R Van Schuylenbergh and Ren{\'e} J. Dom and Erik A. Richter and Peter Hespel},
  journal={Journal of applied physiology},
  volume={95 2},
effect of oral creatine supplementation (CR; 5 g/day) in conjunction with exercise training on physical fitness was investigated in men between 55 and 75 yr of age (n = 46). [] Key Method A double-blind randomized placebo-controlled (PL) trial was performed over a 6-mo period. Furthermore, a subgroup (n = 20) completed a 1-yr follow-up. The training program consisted of cardiorespiratory endurance training as well as moderate resistance training (2-3 sessions/wk).

Figures and Tables from this paper

Effect of ceasing creatine supplementation while maintaining resistance training in older men.

Withdrawal from Cr had no effect on the rate of strength, endurance, and loss of lean tissue mass with 12 weeks of reduced-volume training.

Controlled Trial on the Effects of Creatine Supplementation on Muscle Mass and Function among Older Women Subjected to Resistance Training

Creatine supplementation had no effect on muscle mass or function in older women subjected to resistance training and compliance with training and the supplement was over 80%.

Long-term creatine supplementation improves muscular performance during resistance training in older women

The results indicate that long-term creatine supplementation combined with RT improves the ability to perform submaximal-strength functional tasks and promotes a greater increase in maximal strength, fat-free mass and muscle mass in older women.

Low-dose creatine combined with protein during resistance training in older men.

Low-dose creatine combined with protein supplementation increases lean tissue mass and results in a greater relative increase in bench press but not leg press strength, and reduces muscle protein degradation and bone resorption without increasing formaldehyde production.

Effects of creatine supplementation on the onset of neuromuscular fatigue threshold and muscle strength in elderly men and women (64 - 86 years).

Findings suggest that 14 days of CR supplementation may increase upper body grip strength and increase physical working capacity by delaying neuromuscular fatigue in the elderly men and women in this study.

Resistance Training With Creatine Monohydrate Improves Upper-Body Strength in Patients With Parkinson Disease: A Randomized Trial

It is demonstrated that creatine supplementation can enhance the benefits of resistance training in patients with PD and significant Group × Time interactions for chest press strength and biceps curl strength were revealed.


In elderly women, short-term oral creatine supplementation does not improve endurance capacity but increases the ability to perform lower-body functional living tasks involving rapid movements.

Creatine supplementation post-exercise does not enhance training-induced adaptations in middle to older aged males

Post-exercise ingestion of creatine monohydrate does not provide greater enhancement of body composition and muscle strength compared to resistance training alone in middle to older males.

The effects of supplementation with creatine and protein on muscle strength following a traditional resistance training program in middle-aged and older men

Resistance training in middle-aged and older men significantly increased muscular strength and added muscle mass with no additional benefits from creatine and/or protein supplementation.

The Effects of 'High-Low' Resistance Training and Creatine Supplementation in Aging Adults

Results showed that high- low resistance training improved lean tissue mass, muscle strength, endurance and tasks of functionality and the addition of creatine to high-low resistance training significantly increased body mass andLean tissue mass compared to placebo.



Creatine supplementation combined with resistance training in older men.

Creatine supplementation, when combined with resistance training, increases lean tissue mass and improves leg strength, endurance, and average power in men of mean age 70 yr.

Long-term creatine intake is beneficial to muscle performance during resistance training.

It is concluded that long-term creatine supplementation enhances the progress of muscle strength during resistance training in sedentary females.

Effects of 30 days of creatine ingestion in older men

The data suggest that 30 days of Cr-supplementation may have a beneficial effect on reducing muscle fatigue in men over the age of 60 years, but it does not affect body composition or strength.

Creatine supplementation enhances isometric strength and body composition improvements following strength exercise training in older adults.

This study confirms that supervised heavy resistance exercise training can safely increase muscle strength and functional capacity in older adults and the addition of CrM supplementation to the exercise stimulus enhanced the increase in total and fat-free mass, and gains in several indices of isometric muscle strength.

Effects of oral creatine supplementation on muscular strength and body composition.

Creatine supplementation during arm flexor strength training lead to greater increases in arm Flexor muscular strength, upper arm muscle area, and fat-free mass than strength training alone.

Performance and muscle fiber adaptations to creatine supplementation and heavy resistance training.

Creatine supplementation enhanced fat-free mass, physical performance, and muscle morphology in response to heavy resistance training, presumably mediated via higher quality training sessions.

Creatine supplementation improves muscular performance in older men.

7 d of creatine supplementation is effective at increasing several indices of muscle performance, including functional tests in older men without adverse side effects, and may be a useful therapeutic strategy for older adults to attenuate loss in muscle strength and performance of functional living tasks.

No effect of heavy resistance training and creatine supplementation on blood lipids.

In healthy men, a 12-week heavy resistance training program, with or without creatine supplementation, did not significantly influence serum lipid profiles, subjective reports of body functioning, or serum creatinine concentrations.

Comparison of creatine ingestion and resistance training on energy expenditure and limb blood flow.

This study determined the effects of 28 days of oral creatine ingestion alone and with resistance training on resting metabolic rate (RMR), body composition, muscular strength (1RM), and limb blood flow (LBF) and suggest that the 28- addition of creatine to supplementation and resistance training significantly increases body mass, muscular mass, and resting cholesterol and resting blood flow.

Strength training and determinants of VO2max in older men.

The data suggest that the small increase in leg cycle VO2max in older men may be due to adaptations in oxidative capacity and increased mass of the strength-trained muscles.