Effects of crack cocaine on neurocognitive function.

  title={Effects of crack cocaine on neurocognitive function.},
  author={Anne L Hoff and Henry J Riordan and Lorna Morris and V L Cestaro and Mary Wieneke and Rachel Alpert and Gene Jack Wang and N. D. Volkow},
  journal={Psychiatry research},
  volume={60 2-3},
Because crack cocaine appears to have a preferential effect on the metabolic and electrophysiological activity of the frontal and temporal regions of the brain (Pascual-Leone et al., 1991a, 1991b; Volkow, 1992), we hypothesized that cognitive measures of those regions would be impaired in crack cocaine users relative to measures in normal volunteers. We used logistic regression to determine the relationship of cocaine usage to neuropsychological test performance. We compared 38 patients with an… CONTINUE READING