Effects of copper oxide nanoparticles and copper ions to zebrafish (Danio rerio) cells, embryos and fry.

@article{Thit2017EffectsOC,
  title={Effects of copper oxide nanoparticles and copper ions to zebrafish (Danio rerio) cells, embryos and fry.},
  author={Amalie Thit and Lars Michael Skjolding and Henriette Selck and Joachim Sturve},
  journal={Toxicology in vitro : an international journal published in association with BIBRA},
  year={2017},
  volume={45 Pt 1},
  pages={
          89-100
        }
}
The use of engineered metal nanoparticles (NPs) is continuously increasing and so is the need for information regarding their toxicity. This study compares the toxicity of CuO NPs with ionic Cu in three zebrafish model systems; zebrafish hepatoma cell line (ZFL), fish embryo toxicity test (FET) and fry locomotion. In the ZFL tests, no significant cytotoxicity (cell death, decreased metabolic or cell membrane integrity) was detected for either treatment, though both significantly affected… CONTINUE READING

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