Effects of controlled-release metoprolol on total mortality, hospitalizations, and well-being in patients with heart failure: the Metoprolol CR/XL Randomized Intervention Trial in congestive heart failure (MERIT-HF). MERIT-HF Study Group.

Abstract

CONTEXT Results from recent studies on the effects of beta1-blockade in patients with heart failure demonstrated a 34% reduction in total mortality. However, the effect of beta1-blockade on the frequency of hospitalizations, symptoms, and quality of life in patients with heart failure has not been fully explored. OBJECTIVE To examine the effects of the… (More)

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@article{Hjalmarson2000EffectsOC, title={Effects of controlled-release metoprolol on total mortality, hospitalizations, and well-being in patients with heart failure: the Metoprolol CR/XL Randomized Intervention Trial in congestive heart failure (MERIT-HF). MERIT-HF Study Group.}, author={A. C. Hjalmarson and Sidney Goldstein and Bj{\"{o}rn Fagerberg and Hans Wedel and Finn Waagstein and John Kjekshus Kjekshus and John Wikstrand and Dia el Allaf and Jir{\'i} V{\'i}tovec and Jan Aldershvile and Matti O Halinen and Rainer Dietz and Karl - Ludwig Neuhaus and Andr{\'a}s J{\'a}nosi and Gestur Thorgeirsson and Peter H. J. M. Dunselman and Lars Gullestad and Jerzy Kuch and Johan Herlitz and Peter Rickenbacher and Stephen G. Ball and Silvia Gottlieb and Prakash C. Deedwania}, journal={JAMA}, year={2000}, volume={283 10}, pages={1295-302} }