Effects of continuous localized infusion of granulocyte-macrophage colony-stimulating factor and inoculations of irradiated glioma cells on tumor regression.

@article{Wallenfriedman1999EffectsOC,
  title={Effects of continuous localized infusion of granulocyte-macrophage colony-stimulating factor and inoculations of irradiated glioma cells on tumor regression.},
  author={Margaret A. Wallenfriedman and John A. Conrad and Lance DelaBarre and Patrick C Graupman and Gabriel S. Lee and Margaret Garwood and Dale S Gregerson and Walter C Jean and Walter A. Hall and Walter C. Low},
  journal={Journal of neurosurgery},
  year={1999},
  volume={90 6},
  pages={1064-71}
}
OBJECT Glioblastoma multiforme (GBM) is a malignant tumor of the central nervous system that directly suppresses immunological defenses in vitro and in vivo. The authors used the peripheral delivery of continuously infused granulocyte-macrophage colony-stimulating factor (GM-CSF) in the presence of irradiated tumor antigens as a tumor-specific stimulant to… CONTINUE READING