Effects of compromising agents on candidosis in mice with persistent infections initiated in infancy.

@article{Guentzel1982EffectsOC,
  title={Effects of compromising agents on candidosis in mice with persistent infections initiated in infancy.},
  author={M N Guentzel and Claudia Siklody Herrera},
  journal={Infection and immunity},
  year={1982},
  volume={35 1},
  pages={222-8}
}
Oral-intragastric inoculation of infant CFW mice with Candida albicans, leading either to lethality or to persistent infection of long duration, provides a useful model for study of the host-pathogen interrelationships in candidosis. Mice were most susceptible to the lethal effects of challenge when 4 to 6 days of age, increasingly resistant up to 10 to 11 days, and then resistant to doses of C. albicans lethal for the younger animals. Older mice harboring persistent infections of the… CONTINUE READING
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