Effects of competitive and non-competitiveN-methyl-d-aspartate (NMDA) antagonists in squirrel monkeys trained to discriminated-CPPene (SDZ EAA 494) from vehicle

@article{Wiley1994EffectsOC,
  title={Effects of competitive and non-competitiveN-methyl-d-aspartate (NMDA) antagonists in squirrel monkeys trained to discriminated-CPPene (SDZ EAA 494) from vehicle},
  author={Jenny L Wiley and Robert L. Balster},
  journal={Psychopharmacology},
  year={1994},
  volume={116},
  pages={266-272}
}
Drug discrimination studies have proven useful for comparing and contrasting the behavioral effects of site-selectiveN-methyl-d-aspartate (NMDA) antagonists. This study examined the effects of competitive and non-competitive NMDA antagonists in squirrel monkeys trained to discriminate 1 mg/kgd-CPPene [d-3-(2-carboxypiperazine-4-yl)-1-propenyl-1-phosphonic acid; SDZ EAA 494] from vehicle in a two-lever drug discrimination procedure. Results show thatd-CPPene and several other competitive NMDA… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 46 references

NMDA antagonists : a novel class of anxiolytics ?

  • JL Wiley, RL Balster
  • 1993

Pharmacological profile of NPC 17742

  • JW Ferkany, GS Hamilton, +7 authors EW Karbon
  • [2R, 4R,
  • 1993
2 Excerpts

NMDA receptor

  • CK Park, J McCulloch, JK Kang, CR Choi
  • 1992
1 Excerpt

Preclinical evaluation of N - methyl - D - aspartate antagonists for antianxiety effects : a review

  • JL Wiley, RL Balster
  • 1992

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