Effects of combined exposure to aluminium and ethanol on food intake, motor behaviour and a few biochemical parameters in pubertal rats.

@article{Rajasekaran2000EffectsOC,
  title={Effects of combined exposure to aluminium and ethanol on food intake, motor behaviour and a few biochemical parameters in pubertal rats.},
  author={Rajasekaran},
  journal={Environmental toxicology and pharmacology},
  year={2000},
  volume={9 1-2},
  pages={25-30}
}
  • Rajasekaran
  • Published 2000 in Environmental toxicology and pharmacology
Combined daily administration of aluminium chloride (260 mg/kg, oral) and ethanol (2 g/kg, oral), to pubertal male rats for 30 days was found to significantly decrease food intake, body weight gain and serum protein levels. Spontaneous motor activity and rota-rod motor coordination were also significantly impaired. Acetylcholinesterase activity was significantly diminished in the cerebrum and cerebellum. The results obtained in the present study are suggestive of a potentiation of cholinotoxic… CONTINUE READING