Effects of combined exercise and progesterone treatments on cocaine seeking in male and female rats

@article{Zlebnik2014EffectsOC,
  title={Effects of combined exercise and progesterone treatments on cocaine seeking in male and female rats},
  author={Natalie E Zlebnik and Amy T. Saykao and Marilyn Carroll},
  journal={Psychopharmacology},
  year={2014},
  volume={231},
  pages={3787-3798}
}
BackgroundIndividually, both treatment with progesterone and concurrent access to an exercise wheel reduce cocaine self-administration under long-access conditions and suppress cocaine-primed reinstatement in female rats. In the present study, wheel running and progesterone (alone and combined) were assessed for their effects on reinstatement of cocaine-seeking primed by yohimbine, cocaine, and cocaine-paired cues.MethodsMale and female rats were implanted with an intravenous catheter and… CONTINUE READING
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