Effects of coenzyme Q10 in early Parkinson disease: evidence of slowing of the functional decline.

@article{Shults2002EffectsOC,
  title={Effects of coenzyme Q10 in early Parkinson disease: evidence of slowing of the functional decline.},
  author={Clifford W. Shults and David Oakes and Karl K Kieburtz and M. Flint Beal and Richard Weber Haas and Sandy Plumb and Jorge L. Juncos and John Nutt and Ira Shoulson and Jennifer L. Carter and Katie Kompoliti and Joel S. Perlmutter and Stephen G. Reich and Matthew E. Stern and Ray L. Watts and Roger M. Kurlan and Eric Steven Molho and Madaline Harrison and Mark F. Lew},
  journal={Archives of neurology},
  year={2002},
  volume={59 10},
  pages={
          1541-50
        }
}
BACKGROUND Parkinson disease (PD) is a degenerative neurological disorder for which no treatment has been shown to slow the progression. OBJECTIVE To determine whether a range of dosages of coenzyme Q10 is safe and well tolerated and could slow the functional decline in PD. DESIGN Multicenter, randomized, parallel-group, placebo-controlled, double-blind, dosage-ranging trial. SETTING Academic movement disorders clinics. PATIENTS Eighty subjects with early PD who did not require… CONTINUE READING
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