Effects of coenzyme Q(10) administration on its tissue concentrations, mitochondrial oxidant generation, and oxidative stress in the rat.

@article{Kwong2002EffectsOC,
  title={Effects of coenzyme Q(10) administration on its tissue concentrations, mitochondrial oxidant generation, and oxidative stress in the rat.},
  author={Linda K. Kwong and Sergey Kamzalov and Igor Rebrin and Anne-C{\'e}cile V. Bayne and Chandan K Jana and Paul Morris and Michael J. Forster and Rajindar S. Sohal},
  journal={Free radical biology & medicine},
  year={2002},
  volume={33 5},
  pages={627-38}
}
Coenzyme Q (CoQ(10)) is a component of the mitochondrial electron transport chain and also a constituent of various cellular membranes. It acts as an important in vivo antioxidant, but is also a primary source of O(2)(-*)/H(2)O(2) generation in cells. CoQ has been widely advocated to be a beneficial dietary adjuvant. However, it remains controversial whether oral administration of CoQ can significantly enhance its tissue levels and/or can modulate the level of oxidative stress in vivo. The… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 55 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 46 references

Similar Papers

Loading similar papers…