Effects of clonidine, prazosin and phentolamine on heart rate and coronary sinus catecholamine concentration during cardioaccelerator nerve stimulation in spinal dogs.

@article{Cavero1979EffectsOC,
  title={Effects of clonidine, prazosin and phentolamine on heart rate and coronary sinus catecholamine concentration during cardioaccelerator nerve stimulation in spinal dogs.},
  author={Icilio Cavero and Trevor Dennis and F M Lefevre-Borg and P Perrot and Alan G Roach and Bernard Scatton},
  journal={British journal of pharmacology},
  year={1979},
  volume={67 2},
  pages={283-92}
}
1 In spinal dogs, continuous electrical stimulation of the cardioaccelerator nerve produced a transient rise in aortic blood pressure and a sustained increase in both heart rate and coronary sinus blood flow. The latter effects were accompanied by a significant elevation in the coronary sinus plasma noradrenaline concentration without significant changes in the levels of dopamine and adrenaline. The concentrations of the three catecholamines in thoracic aorta plasma were not significantly… CONTINUE READING

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