Effects of clofibrate treatment on arginine-induced insulin secretion in endogenous hypertriglyceridemia.

@article{Fedele1976EffectsOC,
  title={Effects of clofibrate treatment on arginine-induced insulin secretion in endogenous hypertriglyceridemia.},
  author={Domenico Fedele and Antonio Tiengo and Michele Muggeo and Romano Nosadini and Gaetano Crepaldi},
  journal={Atherosclerosis},
  year={1976},
  volume={25 2-3},
  pages={191-8}
}
Arginine-induced insulin secretion was evaluated in 13 patients with endogenous hypertriglyceridemia (Fredrickson's Type IV) before and after a two-month period of Clofibrate therapy. Clofibrate reduced triglyceride, cholesterol and FFA levels by 68, 28 and 15% respectively and provoked a significant reduction in arginine-induced insulin secretion without… CONTINUE READING