Effects of clbR overexpression on enzyme production in Aspergillus aculeatus vary depending on the cellulosic biomass-degrading enzyme species.

@article{Kunitake2015EffectsOC,
  title={Effects of clbR overexpression on enzyme production in Aspergillus aculeatus vary depending on the cellulosic biomass-degrading enzyme species.},
  author={Emi Kunitake and Ayano Kawamura and Shuji Tani and Shigeo Takenaka and Wataru Ogasawara and Jun-Ichi Sumitani and Takashi Kawaguchi},
  journal={Bioscience, biotechnology, and biochemistry},
  year={2015},
  volume={79 3},
  pages={488-95}
}
ClbR is a Zn(II)2Cys6 transcriptional activator that controls the expression of cellulase-related genes in response to Avicel and cellobiose in Aspergillus aculeatus. A clbR-overexpressing strain (clbR-OE) that expresses the clbR gene at levels sevenfold higher than the control strain sustainably produced xylanolytic and cellulolytic activities during 10-day cultivation of A. aculeatus, enabling synchronization of xylanolytic and cellulolytic activities at a maximum level. However, clbR… CONTINUE READING
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Cooperative regulation of Aspergillus nidulans cellulase genes by transcription factors McmA and ManR/ClrB

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