Effects of cis‐resveratrol on inflammatory murine macrophages: antioxidant activity and down‐regulation of inflammatory genes

  title={Effects of cis‐resveratrol on inflammatory murine macrophages: antioxidant activity and down‐regulation of inflammatory genes},
  author={Jos{\'e} Manuel Leiro and Ezequiel {\'A}lvarez and Juan Alberto Arranz and Reyes Laguna and Eugenio Uriarte and Francisco Orallo},
  journal={Journal of Leukocyte Biology},
This study investigated for the first time the effects of the cis isomer of resveratrol (c‐RESV) on the responses of inflammatory murine peritoneal macrophages, namely on the production of reactive oxygen species (ROS) and reactive nitrogen species (RNS) during the respiratory burst; on the biosynthesis of other mediators of inflammation such prostaglandins; and on the expression of inflammatory genes such as inducible nitric oxide synthase (NOS)‐2 and inducible cyclooxygenase (COX)‐2… 

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