Effects of cilazapril on vascular structure and function in essential hypertension.

@article{Kiowski1996EffectsOC,
  title={Effects of cilazapril on vascular structure and function in essential hypertension.},
  author={Wolfgang Kiowski and Lilly Linder and Reto Nuesch and Benedict Martina},
  journal={Hypertension},
  year={1996},
  volume={27 3 Pt 1},
  pages={
          371-6
        }
}
Hypertension is associated with an altered design of resistance vessels and decreased endothelium-dependent vasodilator response to acetylcholine. A role of angiotensin II in both defects is suggested by animal experiments in which angiotensin-converting enzyme inhibition reverted structural and functional changes. We investigated the effects of 20 weeks of therapy with the angiotensin-converting enzyme inhibitor cilazapril (5 mg twice daily) on the endothelium-dependent response to brachial… CONTINUE READING
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