Effects of cigarette smoking on the angiographic evolution of coronary atherosclerosis. A Canadian Coronary Atherosclerosis Intervention Trial (CCAIT) Substudy. CCAIT Study Group.

@article{Waters1996EffectsOC,
  title={Effects of cigarette smoking on the angiographic evolution of coronary atherosclerosis. A Canadian Coronary Atherosclerosis Intervention Trial (CCAIT) Substudy. CCAIT Study Group.},
  author={David K Waters and Jacques Lesp{\'e}rance and Peter Gladstone and Stephen J. Boccuzzi and T Kevin Cook and R Hudgin and G Krip and Lyall A. J. Higginson},
  journal={Circulation},
  year={1996},
  volume={94 4},
  pages={614-21}
}
BACKGROUND Although smoking increases both the risk of developing coronary disease and the risk of coronary events in patients with known coronary atherosclerosis, the effect of smoking on the evolution of coronary atherosclerosis as assessed by serial angiography is poorly defined. METHODS AND RESULTS Ninety smokers with coronary atherosclerosis shown on a recent angiogram and with fasting cholesterol levels between 220 and 300 mg/dL were enrolled in a randomized, double-blind, placebo… CONTINUE READING