Effects of cigarette smoking on mucin production in human middle ear epithelial cells.

  title={Effects of cigarette smoking on mucin production in human middle ear epithelial cells.},
  author={Jae-Gu Cho and J Woo and Heung-Man Lee and Hak Hyun Jung and Soon-Jae Hwang and Sungwon Chae},
  journal={International journal of pediatric otorhinolaryngology},
  volume={73 10},
OBJECTIVE Otitis media (OM) is the most common disease in preschool age children related to passive cigarette smoking as risk factor. In this study, we investigate whether the cigarette smoking can induce the inflammation in human middle ear epithelial cell, and cigarette smoke-induced inflammation can increase the expression of MUC5AC gene and protein that was known to play an important role in OM with effusion. METHODS After treatment of cigarette smoke solution (CSS) on immortalized human… CONTINUE READING
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