Effects of cigarette smoke on the Meckel's cartilage of rat fetus: morphologic, morphometric and stereologic study.

@article{Brandini2005EffectsOC,
  title={Effects of cigarette smoke on the Meckel's cartilage of rat fetus: morphologic, morphometric and stereologic study.},
  author={Daniela Atili Brandini and Miguel Angel Sala and Ruberval Armando Lopes and Marisa Semprini and Mary Garcia Duarte Contrera},
  journal={Brazilian dental journal},
  year={2005},
  volume={16 1},
  pages={62-6}
}
The purpose of this study was to investigate the effects of cigarette smoke on the development of the embryo mandible (Meckel's) cartilage in rat fetuses. When inhaled by female Wistar rats between the 9th and the 12th day of pregnancy, cigarette smoke (5 cigarettes a day) caused intrauterine growth retardation, providing smaller fetuses and placentas. In fetuses from the experimental group, the histopathologic examination revealed a poorly developed Meckel's cartilage with smaller… CONTINUE READING

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