Effects of chronic stress and phenytoin on the long-term potentiation (LTP) in rat hippocampal CA1 region.

@article{Zheng2004EffectsOC,
  title={Effects of chronic stress and phenytoin on the long-term potentiation (LTP) in rat hippocampal CA1 region.},
  author={Hui Zheng and Quan Yang and Chong-Tao Xu},
  journal={Acta biochimica et biophysica Sinica},
  year={2004},
  volume={36 5},
  pages={375-8}
}
To investigate the changes of LTP in hippocampal CA1 region induced by chronic stress and the effect of phenytoin on them, thirty-two adult male Sprague-Dawley rats were randomly divided equally into four groups: control group, control-phenytoin group, stress-saline group and stress-phenytoin group. Isolated hippocampal slices of rats were used to observe the changes of long-term potentiation (LTP) in hippocampal CA1 field using electrophysiological technique. Amplitude of population spike (PS… CONTINUE READING