Effects of chronic stress and interleukin-10 gene polymorphisms on antibody response to tetanus vaccine in family caregivers of patients with Alzheimer's disease.

@article{Li2007EffectsOC,
  title={Effects of chronic stress and interleukin-10 gene polymorphisms on antibody response to tetanus vaccine in family caregivers of patients with Alzheimer's disease.},
  author={Jian Li and Linda G Cowden and Janice D. King and David A Briles and Harry W. Schroeder and Alan B. Stevens and Rodney T. Perry and Zuomin Chen and Micah S. Simmons and Howard W. Wiener and Hemant K. Tiwari and Lindy E. Harrell and Rodney C. P. Go},
  journal={Psychosomatic medicine},
  year={2007},
  volume={69 6},
  pages={551-9}
}
OBJECTIVE To assess the effects of psychological stress on the antibody response to tetanus vaccine adjusting for cytokine gene polymorphisms and other nongenetic factors in caregivers of patients with Alzheimer's disease (AD). METHODS A family-based follow-up study was conducted in 119 spouses and offspring of community-dwelling patients with AD. Psychological stress was measured by the Perceived Stress Scale (PSS) and the Center for Epidemiologic Studies Depression (CES-D) scale at baseline… CONTINUE READING

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