Effects of chronic oral rimonabant administration on energy budgets of diet-induced obese C57BL/6 mice.

@article{Zhang2012EffectsOC,
  title={Effects of chronic oral rimonabant administration on energy budgets of diet-induced obese C57BL/6 mice.},
  author={Li-na Zhang and Yuko Gamo and Rachel E Sinclair and Sharon E. Mitchell and David G A Morgan and John C. Clapham and John R Speakman},
  journal={Obesity},
  year={2012},
  volume={20 5},
  pages={954-62}
}
The endocannabinoids have been recognized as an important system involved in the regulation of energy balance. Rimonabant (SR141716), a selective inverse agonist of cannabinoid receptor 1 (CB1), has been shown to cause weight loss. However, its suppressive impact on food intake is transient, indicating a likely additional effect on energy expenditure. To examine the effects of rimonabant on components of energy balance, we administered rimonabant or its vehicle to diet-induced obese (DIO) C57BL… CONTINUE READING
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Interlaboratory comparison of different analytical techniques for the determination of oxygen-18 abundance

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  • Anal Chem
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