Effects of chronic opioid antagonism on gonadotrophin and ovarian sex steroid secretion during the luteal phase.

Abstract

OBJECTIVES Since short-term opioid antagonism increases LH pulsatility during the luteal phase in women, we postulated that prolonged opioid antagonism may also accelerate the LH secretory episodes at this time. If so, the functional and temporal links between secretory episodes of pituitary LH and oestradiol (E2) and progesterone (P) release from the… (More)

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