Effects of chronic nicotine administration and its withdrawal on striatal FosB/ΔFosB and c-Fos expression in rats and mice

@article{Marttila2006EffectsOC,
  title={Effects of chronic nicotine administration and its withdrawal on striatal FosB/$\Delta$FosB and c-Fos expression in rats and mice},
  author={Kristiina Marttila and Helena Raattamaa and Liisa Ahtee},
  journal={Neuropharmacology},
  year={2006},
  volume={51},
  pages={44-51}
}

Opiate Sensitization Induces FosB/ΔFosB Expression in Prefrontal Cortical, Striatal and Amygdala Brain Regions

Intermittent morphine pre-treated days produced a significant induction of FosB/ΔFosB, measured on day 16, in multiple brain regions including prelimbic (PL) and infralimbic (IL) cortex, nucleus accumbens (NAc) core, dorsomedial caudate-putamen (CPU), basolateral amygdala (BLA) and central nucleus of the amygdala (CNA) but not in a motor cortex control region.

Pleiotropic impact of constitutive fosB inactivation on nicotine-induced behavioral alterations and stress-related traits in mice.

The results suggest that the constitutive absence of fosB has a pleiotropic influence on the behavioral effects of repeated or prolonged nicotine administration and on stress-related behavioral traits in mice.

Baclofen prevented the changes in c‐Fos and brain‐derived neutrophic factor expressions during mecamylamine‐precipitated nicotine withdrawal in mice

A relationship between BAC's preventive effect of the expression of NIC withdrawal signs, and its ability to restore the changes in c‐Fos and BDNF expression, observed in specific brain areas of NIC‐withdrawn mice are suggested.

DeltaFosB accumulation in ventro‐medial caudate underlies the induction but not the expression of behavioral sensitization by both repeated amphetamine and stress

The hypothesis that a common neuroadaptive process involving DeltaFosB accumulation in the ventro‐medial caudate underlies the induction but not the expression of behavioral sensitization by different conditions is supported.
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