Effects of chronic manipulations of dietary choline on locomotor activity, discrimination learning and cortical acetylcholine release in aging adult fisher 344 rats

@article{Beninger1984EffectsOC,
  title={Effects of chronic manipulations of dietary choline on locomotor activity, discrimination learning and cortical acetylcholine release in aging adult fisher 344 rats},
  author={Richard J. Beninger and Spencer A. Tighe and Khem H. Jhamandas},
  journal={Neurobiology of Aging},
  year={1984},
  volume={5},
  pages={29-34}
}
Dietary levels of choline have been shown to influence central cholinergic neurotransmission. To further examine the behavioral and neurochemical effects of dietary choline, adult Fisher 344 rats were maintained on choline deficient (n = 6), enriched (n = 6) or usual lab chow (n = 6) diets for 38 weeks. During 14 weeks of free access to these diets, controls gained little weight whereas the deficient group increased and the enriched group decreased. For the remaining 24 weeks the weights of all… Expand
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