Effects of chronic intermittent hypoxia on genioglossus in rats

  title={Effects of chronic intermittent hypoxia on genioglossus in rats},
  author={Hanpeng Huang and Xiaofeng Zhang and Ning Ding and Qin Li and Yin Min and Xi-long Zhang},
  journal={Sleep and Breathing},
The objective of this study was to investigate the effects of chronic intermittent hypoxia (CIH) on genioglossal ultrastructure and mitochondrial function as well as the intervention role of adiponectin (Ad). Forty-two Wistar rats were randomly divided into three groups with 14 rats in each. Rats in group A were kept breathing normal air, while rats in both groups B and C received the same CIH environment (a 2-min cycle, 1 min on, 1 min off with a nadir O2 at 4–5%, 8 h/day for successive 5… CONTINUE READING


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