Effects of chronic exercise and treatment with the antipsychotic drug olanzapine on hippocampal volume in adult female rats

@article{Barr2013EffectsOC,
  title={Effects of chronic exercise and treatment with the antipsychotic drug olanzapine on hippocampal volume in adult female rats},
  author={Alasdair M Barr and Che Hsuan Wu and Conrad Tin-Cheung Wong and Christa Hercher and Elfi T{\"o}pfer and Heidi Noel Boyda and Ric M Procyshyn and William Honer and Clare L. Beasley},
  journal={Neuroscience},
  year={2013},
  volume={255},
  pages={147-157}
}
Numerous studies have reported that the hippocampus in schizophrenia patients is reduced in volume compared to the normal population. Antipsychotic medications have had mixed benefits in maintaining hippocampal volume or reversing volume loss. Recent evidence indicates that routine aerobic exercise represents a promising intervention for reversing hippocampal loss and cognitive deficits. In the present study, we measured the effects of chronic treatment with olanzapine and daily exercise on the… CONTINUE READING
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