Effects of chronic excess salt ingestion. Modification of experimental hypertension in the rat by variations in the diet.

@article{Dahl1968EffectsOC,
  title={Effects of chronic excess salt ingestion. Modification of experimental hypertension in the rat by variations in the diet.},
  author={Lewis K. Dahl and Knud D. Knudsen and Martha Heine and G J Leitl},
  journal={Circulation research},
  year={1968},
  volume={22 1},
  pages={11-8}
}
A strain of rats that will predictably develop experimental hypertension by means of different techniques was used to study NaCl-induced hypertension. Observations were continued for 1 year after weaning unless death intervened. Among groups of rats on 0.4, 1, 2, 4, and 8% NaCl chow, respectively, blood pressures generally rose as dietary NaCl increased. Average blood pressures ranged from 146.8 mm Hg in the group on the lowest, to 210.2 mm Hg in the group with the highest NaCl intakes… CONTINUE READING

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