Effects of chronic ethanol treatment and aging on brain phosphoinositide turnover and adenylate cyclase activity.

Abstract

Inositol phosphate accumulation and adenylate cyclase activity were investigated in the cortex of young and aged ethanol-treated rats. Three months of ethanol treatment of young rats decreased maximal stimulation of inositol phosphate accumulation by carbachol by 26%, from 494 +/- 76% of basal turnover in control animals to 396 +/- 54% in ethanol-treated… (More)

Topics

Cite this paper

@article{Pietrzak1990EffectsOC, title={Effects of chronic ethanol treatment and aging on brain phosphoinositide turnover and adenylate cyclase activity.}, author={Eva Pietrzak and Peter A. Wilce and Brian C Shanley}, journal={Neurochemistry international}, year={1990}, volume={17 4}, pages={593-8} }