Effects of chronic d-amphetamine administration on the reinforcing strength of cocaine in rhesus monkeys

@article{Czoty2010EffectsOC,
  title={Effects of chronic d-amphetamine administration on the reinforcing strength of cocaine in rhesus monkeys},
  author={Paul W. Czoty and Jennifer L. Martelle and Michael A. Nader},
  journal={Psychopharmacology},
  year={2010},
  volume={209},
  pages={375-382}
}
Agonist medications have been proven effective in treating opioid and nicotine dependence; results from clinical studies suggest that the indirect dopamine agonist d-amphetamine may reduce cocaine abuse. In preclinical studies, chronic d-amphetamine treatment decreased ongoing cocaine self-administration. The present study extended previous results by determining effects of chronic d-amphetamine treatment on the reinforcing strength of cocaine under conditions in which access to cocaine was… CONTINUE READING
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