Effects of chronic alcohol and repeated deprivations on dopamine D1 and D2 receptor levels in the extended amygdala of inbred alcohol-preferring rats.

@article{Sari2006EffectsOC,
  title={Effects of chronic alcohol and repeated deprivations on dopamine D1 and D2 receptor levels in the extended amygdala of inbred alcohol-preferring rats.},
  author={Youssef Sari and Richard L. Bell and Feng Chao Zhou},
  journal={Alcoholism, clinical and experimental research},
  year={2006},
  volume={30 1},
  pages={46-56}
}
BACKGROUND Dopaminergic (DA) activity in the extended amygdala (EA) has been known to play a pivotal role in mediating drug and alcohol addiction. Alterations of DA activity within the EA after chronic exposure to alcohol or substances of abuse are considered a major mechanism for the development of alcoholism and addiction. To date, it is not clear how different patterns of chronic alcohol drinking affect DA receptor levels. Therefore, the current studies investigated the effects of chronic… CONTINUE READING